> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > HRH2 / Histamine H2 Receptor Antibody (Cytoplasmic Domain)Brand |
Leading Biology | Catalog Number |
APR16717G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality HRH2 / Histamine H2 Receptor antibody (Cytoplasmic Domain).
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Molecular Weight |
40kDa
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Cellular Localization |
Antigen Cellular Localization:
Cell membrane; Multi-pass membrane protein.
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Host |
Rabbit
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Species Reactivity |
Human, Monkey
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Target |
Human HRH2 / Histamine H2 Receptor. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
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GeneID |
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UniProt ID |
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Function |
The H2 subclass of histamine receptors mediates gastric acid secretion. Also appears to regulate gastrointestinal motility and intestinal secretion. Possible role in regulating cell growth and differentiation. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and, through a separate G protein-dependent mechanism, the phosphoinositide/protein kinase (PKC) signaling pathway (By similarity).
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Summary |
The H2 subclass of histamine receptors mediates gastric acid secretion. Also appears to regulate gastrointestinal motility and intestinal secretion. Possible role in regulating cell growth and differentiation. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and, through a separate G protein-dependent mechanism, the phosphoinositide/protein kinase (PKC) signaling pathway (By similarity).
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Form |
Liquid |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
IHC-P
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Dilution |
IHC-P (38 μg/ml)
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Synonyms |
Histamine H2 receptor, H2R, HH2R, Gastric receptor I, HRH2
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Images |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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