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MLX Antibody (internal region)

Catalog # Availability Size / Price Inquiry
APR08459G 0.1 mg / $495

MLX Antibody (internal region)

Brand

Leading Biology

Catalog Number

APR08459G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality MLX antibody (internal region).

Molecular Weight

33300 Da

Cellular Localization

Antigen Cellular Localization: Isoform Alpha: Cytoplasm. Note=Found predominantly in the cytoplasm Isoform Gamma: Nucleus. Note=Found predominantly in the nucleus

Host

Goat

Species Reactivity

Human

Isotype

IgG

Symbol

BHLHD13, TCFL4

GeneID

UniProt ID

Function

Transcription regulator. Forms a sequence-specific DNA- binding protein complex with MAD1, MAD4, MNT, WBSCR14 and MLXIP which recognizes the core sequence 5'-CACGTG-3'. The TCFL4-MAD1, TCFL4-MAD4, TCFL4-WBSCR14 complexes are transcriptional repressors. Plays a role in transcriptional activation of glycolytic target genes. Involved in glucose-responsive gene regulation.

Summary

This antibody is expected to recognize all three reported isoforms (NP_937848.1; NP_937847.1; NP_733752.1).

Form

0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

IHC, E

Synonyms

Max-like protein X, Class D basic helix-loop-helix protein 13, bHLHd13, Max-like bHLHZip protein, Protein BigMax, Transcription factor-like protein 4, MLX, BHLHD13, TCFL4

Images

APR08459G (3.8 μg/ml) staining of paraffin embedded Human Placenta. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.

Specification

Quantity

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