> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > Dual oxidase 1 Antibody (internal region)Brand |
Leading Biology | Catalog Number |
APR07628G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Dual oxidase 1 antibody (internal region).
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Molecular Weight |
177235 Da
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Cellular Localization |
Antigen Cellular Localization:
Apical cell membrane; Multi- pass membrane protein. Note=Localizes to the apical membrane of epithelial cells
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Host |
Goat
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Species Reactivity |
Human
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Isotype |
IgG
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Symbol |
DUOX, LNOX1, THOX1
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GeneID |
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UniProt ID |
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Function |
Generates hydrogen peroxide which is required for the activity of thyroid peroxidase/TPO and lactoperoxidase/LPO. Plays a role in thyroid hormones synthesis and lactoperoxidase-mediated antimicrobial defense at the surface of mucosa. May have its own peroxidase activity through its N-terminal peroxidase-like domain.
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Summary |
This antibody is expected to recognise both reported isoforms (NP_059130.2 ; NP_787954.1) which are identical;
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Form |
0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
IHC, E
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Synonyms |
Dual oxidase 1, 1.11.1.-, 1.6.3.1, Large NOX 1, Long NOX 1, NADPH thyroid oxidase 1, Thyroid oxidase 1, DUOX1, DUOX, LNOX1, THOX1
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Images |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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