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Location: Home > Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > Phorbolin 1 / APOBEC3A Antibody (internal region)

Phorbolin 1 / APOBEC3A Antibody (internal region)

Catalog # Availability Size / Price Inquiry
APR09119G 0.1 mg / $495

Phorbolin 1 / APOBEC3A Antibody (internal region)

Brand

Leading Biology

Catalog Number

APR09119G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Phorbolin 1 / APOBEC3A antibody (internal region).

Molecular Weight

23012 Da

Cellular Localization

Antigen Cellular Localization: Nucleus. Cytoplasm.

Host

Goat

Species Reactivity

Human

Isotype

IgG

GeneID

UniProt ID

Function

DNA deaminase (cytidine deaminase) with restriction activity against viruses, foreign DNA and mobility of retrotransposons. Exhibits antiviral activity against adeno- associated virus (AAV) and human T-cell leukemia virus type 1 (HTLV-1) and may inhibit the mobility of LTR and non-LTR retrotransposons. Selectively targets single-stranded DNA and can deaminate both methylcytosine and cytosine in foreign DNA. Can induce somatic hypermutation in the nuclear and mitochondrial DNA. May also play a role in the epigenetic regulation of gene expression through the process of active DNA demethylation.

Form

0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

IHC, E

Synonyms

DNA dC->dU-editing enzyme APOBEC-3A, A3A, 3.5.4.-, Phorbolin-1, APOBEC3A

Images

APR09119G (3.8 μg/ml) staining of paraffin embedded Human Tonsil. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.

Specification

Quantity

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