> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > AGRP / Agouti-related protein Antibody (C-Term)Brand |
Leading Biology | Catalog Number |
APG01607G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality AGRP / Agouti-related protein antibody (C-Term).
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Molecular Weight |
14440 Da
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Cellular Localization |
Antigen Cellular Localization:
Secreted. Golgi apparatus lumen
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Host |
Goat
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Species Reactivity |
Human
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Isotype |
IgG
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Symbol |
AGRT, ART
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GeneID |
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UniProt ID |
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Function |
Plays a role in weight homeostasis. Involved in the control of feeding behavior through the central melanocortin system. Acts as alpha melanocyte-stimulating hormone antagonist by inhibiting cAMP production mediated by stimulation of melanocortin receptors within the hypothalamus and adrenal gland. Has very low activity with MC5R (By similarity). Is an inverse agonist for MC3R and MC4R being able to suppress their constitutive activity. It promotes MC3R and MC4R endocytosis in an arrestin-dependent manner.
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Summary |
This antibody is expected to recognise both reported isoforms (as represented by NP_001129; NP_015531)
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Form |
0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
IHC, E
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Synonyms |
Agouti-related protein, AGRP, AGRT, ART
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Images |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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