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Location: Home > Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > Activin receptor-like kinase 1 Antibody (C-Term)

Activin receptor-like kinase 1 Antibody (C-Term)

Catalog # Availability Size / Price Inquiry
APG01522G 0.1 mg / $495

Activin receptor-like kinase 1 Antibody (C-Term)

Brand

Leading Biology

Catalog Number

APG01522G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Activin receptor-like kinase 1 antibody (C-Term).

Molecular Weight

56124 Da

Cellular Localization

Antigen Cellular Localization: Membrane; Single-pass type I membrane protein

Host

Goat

Species Reactivity

Human

Isotype

IgG

Symbol

ACVRLK1, ALK1

GeneID

UniProt ID

Function

Type I receptor for TGF-beta family ligands BMP9/GDF2 and BMP10 and important regulator of normal blood vessel development. On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. May bind activin as well.

Summary

Please note that this product is not to be confused with the similarly named ALK (anaplastic lymphoma kinase, GeneID 238). Reported variant represent identical protein: NP_000011.2; NP_001070869.1

Form

0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Synonyms

Serine/threonine-protein kinase receptor R3, SKR3, 2.7.11.30, Activin receptor-like kinase 1, ALK-1, TGF-B superfamily receptor type I, TSR-I, ACVRL1, ACVRLK1, ALK1

Images

APG01522G (2 μg/ml) staining of MCF7 lysate (35 μg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Specification

Quantity

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