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SOCS4 Antibody (C-Term)

Catalog # Availability Size / Price Inquiry
AMM07929G 0.1 mg / $495

SOCS4 Antibody (C-Term)

Brand

Leading Biology

Catalog Number

AMM07929G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality SOCS4 antibody (C-Term).

Molecular Weight

50623 Da

Host

Goat

Species Reactivity

Human

Isotype

IgG

Symbol

SOCS7

GeneID

UniProt ID

Function

SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. Substrate-recognition component of a SCF-like ECS (Elongin BC- CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Inhibits EGF signaling by mediating the degradation of the Tyr-phosphorylated EGF receptor/EGFR.

Summary

Both variants represent identical protein (NP_543143.1 and NP_955453.1).

Form

0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

IHC, E

Synonyms

Suppressor of cytokine signaling 4, SOCS-4, Suppressor of cytokine signaling 7, SOCS-7, SOCS4, SOCS7

Images

AMM07929G (3.8 μg/ml) staining of paraffin embedded Human Pancreas. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.

Specification

Quantity

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