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Goat Anti-Tafazzin Antibody

Catalog # Availability Size / Price Inquiry
AMM05140G 0.1 mg / $495

Goat Anti-Tafazzin Antibody

Brand

Leading Biology

Catalog Number

AMM05140G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Goat Anti-Tafazzin antibody.

Molecular Weight

33459 Da

Cellular Localization

Antigen Cellular Localization: Isoform 1: Membrane; Single-pass membrane protein Isoform 3: Membrane; Single-pass membrane protein Isoform 5: Membrane; Single-pass membrane protein Isoform 7: Membrane; Single-pass membrane protein Isoform 9: Cytoplasm.

Host

Goat

Species Reactivity

Human

Isotype

IgG

Symbol

EFE2, G4.5

GeneID

UniProt ID

Function

Some isoforms may be involved in cardiolipin (CL) metabolism.

Summary

This gene encodes a protein that is expressed at high levels in cardiac and skeletal muscle. Mutations in this gene have been associated with a number of clinical disorders including Barth syndrome, dilated cardiomyopathy (DCM), hypertrophic DCM, endocardial fibroelastosis, and left ventricular noncompaction (LVNC). Multiple transcript variants encoding different isoforms have been described. A long form and a short form of each of these isoforms is produced; the short form lacks a hydrophobic leader sequence and may exist as a cytoplasmic protein rather than being membrane-bound. Other alternatively spliced transcripts have been described but the full-length nature of all these transcripts is not known.

Form

0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Synonyms

Tafazzin, Protein G4.5, TAZ, EFE2, G4.5

Images

AMM05140G (0.3 μg/ml) staining of Human Heart lysate (35 μg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Specification

Quantity

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