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Location: Home > Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > Goat Anti-Syntrophin gamma 2 Antibody

Goat Anti-Syntrophin gamma 2 Antibody

Catalog # Availability Size / Price Inquiry
APR12188G 0.1 mg / $495

Goat Anti-Syntrophin gamma 2 Antibody

Brand

Leading Biology

Catalog Number

APR12188G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Goat Anti-Syntrophin gamma 2 antibody.

Molecular Weight

60217 Da

Cellular Localization

Antigen Cellular Localization: Cell membrane, sarcolemma; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton Note=In skeletal muscle, it localizes at the cytoplasmic side of the sarcolemmal membrane

Host

Goat

Species Reactivity

Human

Isotype

IgG

GeneID

UniProt ID

Function

Adapter protein that binds to and probably organizes the subcellular localization of a variety of proteins. May link various receptors to the actin cytoskeleton and the dystrophin glycoprotein complex (By similarity).

Summary

This gene encodes a protein belonging to the syntrophin family. Syntrophins are cytoplasmic peripheral membrane proteins that bind to components of mechanosenstive sodium channels and the extreme carboxy-terminal domain of dystrophin and dystrophin-related proteins. The PDZ domain of this protein product interacts with a protein component of a mechanosensitive sodium channel that affects channel gating. Absence or reduction of this protein product has been associated with Duchenne muscular dystrophy. There is evidence of alternative splicing yet the full-length nature of these variants has not been described.

Form

0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Synonyms

Gamma-2-syntrophin, G2SYN, Syntrophin-5, SYN5, SNTG2

Images

APR12188G (0.3 μg/ml) staining of Human Duodenum lysate (35 μg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Specification

Quantity

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