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Goat Anti-PTPRT Antibody

Catalog # Availability Size / Price Inquiry
APR16369G 0.1 mg / $495

Goat Anti-PTPRT Antibody

Brand

Leading Biology

Catalog Number

APR16369G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Goat Anti-PTPRT antibody.

Molecular Weight

162134 Da

Cellular Localization

Antigen Cellular Localization: Membrane; Single-pass type I membrane protein

Host

Goat

Species Reactivity

Human

Isotype

IgG

Symbol

KIAA0283

GeneID

UniProt ID

Function

May be involved in both signal transduction and cellular adhesion in the CNS.

Summary

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem intracellular catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains a meprin-A5 antigen-PTP (MAM) domain, Ig-like and fibronectin type III-like repeats. The protein domain structure and the expression pattern of the mouse counterpart of this PTP suggest its roles in both signal transduction and cellular adhesion in the central nervous system. Two alternatively spliced transcript variants of this gene, which encode distinct proteins, have been reported.

Form

0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Synonyms

Receptor-type tyrosine-protein phosphatase T, R-PTP-T, 3.1.3.48, Receptor-type tyrosine-protein phosphatase rho, RPTP-rho, PTPRT, KIAA0283

Images

APR16369G staining (0.3 μg/ml) of Human Brain lysate (RIPA buffer, 35 μg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.

Specification

Quantity

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