> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > Goat Anti-PTPRT AntibodyBrand |
Leading Biology | Catalog Number |
APR16369G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Goat Anti-PTPRT antibody.
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Molecular Weight |
162134 Da
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Cellular Localization |
Antigen Cellular Localization:
Membrane; Single-pass type I membrane protein
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Host |
Goat
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Species Reactivity |
Human
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Isotype |
IgG
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Symbol |
KIAA0283
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GeneID |
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UniProt ID |
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Function |
May be involved in both signal transduction and cellular adhesion in the CNS.
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Summary |
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem intracellular catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains a meprin-A5 antigen-PTP (MAM) domain, Ig-like and fibronectin type III-like repeats. The protein domain structure and the expression pattern of the mouse counterpart of this PTP suggest its roles in both signal transduction and cellular adhesion in the central nervous system. Two alternatively spliced transcript variants of this gene, which encode distinct proteins, have been reported.
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Form |
0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, E
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Synonyms |
Receptor-type tyrosine-protein phosphatase T, R-PTP-T, 3.1.3.48, Receptor-type tyrosine-protein phosphatase rho, RPTP-rho, PTPRT, KIAA0283
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Images |
APR16369G staining (0.3 μg/ml) of Human Brain lysate (RIPA buffer, 35 μg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence. |
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Specification |
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Quantity |
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Tel: 1-661-524(LBI)-0262
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