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Goat Anti-PLA2G1B Antibody

Catalog # Availability Size / Price Inquiry
AMM05087G 0.1 mg / $495

Goat Anti-PLA2G1B Antibody

Brand

Leading Biology

Catalog Number

AMM05087G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Goat Anti-PLA2G1B antibody.

Molecular Weight

16360 Da

Cellular Localization

Antigen Cellular Localization: Secreted. Note=secreted from pancreatic acinar cells in its inactive form

Host

Goat

Species Reactivity

Human

Isotype

IgG

Symbol

PLA2, PLA2A, PPLA2

GeneID

UniProt ID

Function

PA2 catalyzes the calcium-dependent hydrolysis of the 2- acyl groups in 3-sn-phosphoglycerides, this releases glycerophospholipids and arachidonic acid that serve as the precursors of signal molecules.

Summary

Phospholipase A2 (EC 3.1.1.4) catalyzes the release of fatty acids from glycero-3-phosphocholines. The best known varieties are the digestive enzymes secreted as zymogens by the pancreas of mammals. Sequences of pancreatic PLA2 enzymes from a variety of mammals have been reported. One striking feature of these enzymes is their close homology to venom phospholipases of snakes. Other forms of PLA2 have been isolated from brain, liver, lung, spleen, intestine, macrophages, leukocytes, erythrocytes, inflammatory exudates, chondrocytes, and platelets (Seilhamer et al., 1986 [PubMed 3028739]) .

Form

0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Synonyms

Phospholipase A2, 3.1.1.4, Group IB phospholipase A2, Phosphatidylcholine 2-acylhydrolase 1B, PLA2G1B, PLA2, PLA2A, PPLA2

Images

AMM05087G (0.01 μg/ml) staining of Human Pancreas lysate (35 μg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

HEK293 overexpressing PLA2G1B (RC216089) and probed with AMM05087G (mock transfection in first lane), tested by Origene.

Specification

Quantity

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