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Location: Home > Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > Goat Anti-Perilipin (C Terminus) Antibody

Goat Anti-Perilipin (C Terminus) Antibody

Catalog # Availability Size / Price Inquiry
AMM05081G 0.1 mg / $495

Goat Anti-Perilipin (C Terminus) Antibody

Brand

Leading Biology

Catalog Number

AMM05081G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Goat Anti-Perilipin (C Terminus) antibody.

Molecular Weight

55990 Da

Cellular Localization

Antigen Cellular Localization: Endoplasmic reticulum. Lipid droplet. Note=Lipid droplet surface- associated

Host

Goat

Species Reactivity

Human

Isotype

IgG

Symbol

PERI, PLIN

GeneID

UniProt ID

Function

Modulator of adipocyte lipid metabolism. Coats lipid storage droplets to protect them from breakdown by hormone- sensitive lipase (HSL). Its absence may result in leanness. Plays a role in unilocular lipid droplet formation by activating CIDEC. Their interaction promotes lipid droplet enlargement and directional net neutral lipid transfer. May modulate lipolysis and triglyceride levels.

Summary

The protein encoded by this gene coats lipid storage droplets in adipocytes, thereby protecting them until they can be broken down by hormone-sensitive lipase. The encoded protein is the major cAMP-dependent protein kinase substrate in adipocytes and, when unphosphorylated, may play a role in the inhibition of lipolysis. Alternatively spliced transcript variants varying in the 5' UTR, but encoding the same protein, have been found for this gene.

Form

0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IF, E

Synonyms

Perilipin-1, Lipid droplet-associated protein, PLIN1, PERI, PLIN

Images

AMM05081G (0.01 μg/ml) staining of Human Adipose lysate (35 μg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

AMM05081G staining of differentiated 3T3-L1 adipocytes. Data kindly provided by Prof. J. Granneman, Detroit, USA

Specification

Quantity

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