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Location: Home > Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > Goat Anti-Pancreatic Polypeptide / PPY Antibody

Goat Anti-Pancreatic Polypeptide / PPY Antibody

Catalog # Availability Size / Price Inquiry
APR16351G 0.1 mg / $495

Goat Anti-Pancreatic Polypeptide / PPY Antibody

Brand

Leading Biology

Catalog Number

APR16351G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Goat Anti-Pancreatic Polypeptide / PPY antibody.

Molecular Weight

10445 Da

Cellular Localization

Antigen Cellular Localization: Secreted.

Host

Goat

Species Reactivity

Human, Mouse

Isotype

IgG

Symbol

PNP

GeneID

UniProt ID

Function

Pancreatic hormone is synthesized in pancreatic islets of Langerhans and acts as a regulator of pancreatic and gastrointestinal functions.

Summary

This gene belongs to the NPY family and it encodes a protein that is synthesized as a 95 aa polypeptide precursor in the pancreatic islets of Langerhans. It is cleaved into two peptide products; the active hormone of 36 aa and an icosapeptide of unknown function. The hormone acts as a regulator of pancreatic and gastrointestinal functions and may be important in the regulation of food intake. Plasma level of this hormone has been shown to be reduced in conditions associated with increased food intake and elevated in anorexia nervosa. In addition, infusion of this hormone in obese rodents has shown to decrease weight gain.

Form

0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

IHC, E

Synonyms

Pancreatic prohormone, Pancreatic polypeptide, PP, Obinepitide, Pancreatic hormone, PH, Pancreatic icosapeptide, PI, PPY, PNP

Images

APR16351G (3 μg/ml) staining of paraffin embedded human pancreas. Microwaved antigen retrieval with Tris/EDTA buffer pH9, HRP-staining.

Specification

Quantity

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