> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > Goat Anti-Pallidin AntibodyBrand |
Leading Biology | Catalog Number |
APR16340G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Goat Anti-Pallidin antibody.
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Molecular Weight |
19744 Da
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Cellular Localization |
Antigen Cellular Localization:
Cytoplasm. Endomembrane system; Peripheral membrane protein. Note=It can exist as a soluble protein as well as a peripheral membrane protein
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Host |
Goat
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Species Reactivity |
Human
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Isotype |
IgG
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Symbol |
PA, PLDN
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GeneID |
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UniProt ID |
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Function |
Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. May play a role in intracellular vesicle trafficking, particularly in the vesicle-docking and fusion process.
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Summary |
The protein encoded by this gene may play a role in intracellular vesicle trafficking. It interacts with Syntaxin 13 which mediates intracellular membrane fusion. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.
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Form |
0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, E
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Synonyms |
Biogenesis of lysosome-related organelles complex 1 subunit 6, BLOC-1 subunit 6, Pallid protein homolog, Pallidin, Syntaxin 13-interacting protein, BLOC1S6, PA, PLDN
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Images |
APR16340G staining (1 μg/ml) of A431 lysate (RIPA buffer, 35 μg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.
HEK293 overexpressing PLDN (RC201514) and probed with APR16340G (mock transfection in first lane), tested by Origene. |
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Specification |
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Quantity |
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