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Goat Anti-Pallidin Antibody

Catalog # Availability Size / Price Inquiry
APR16340G 0.1 mg / $495

Goat Anti-Pallidin Antibody

Brand

Leading Biology

Catalog Number

APR16340G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Goat Anti-Pallidin antibody.

Molecular Weight

19744 Da

Cellular Localization

Antigen Cellular Localization: Cytoplasm. Endomembrane system; Peripheral membrane protein. Note=It can exist as a soluble protein as well as a peripheral membrane protein

Host

Goat

Species Reactivity

Human

Isotype

IgG

Symbol

PA, PLDN

GeneID

UniProt ID

Function

Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. May play a role in intracellular vesicle trafficking, particularly in the vesicle-docking and fusion process.

Summary

The protein encoded by this gene may play a role in intracellular vesicle trafficking. It interacts with Syntaxin 13 which mediates intracellular membrane fusion. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.

Form

0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Synonyms

Biogenesis of lysosome-related organelles complex 1 subunit 6, BLOC-1 subunit 6, Pallid protein homolog, Pallidin, Syntaxin 13-interacting protein, BLOC1S6, PA, PLDN

Images

APR16340G staining (1 μg/ml) of A431 lysate (RIPA buffer, 35 μg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.

HEK293 overexpressing PLDN (RC201514) and probed with APR16340G (mock transfection in first lane), tested by Origene.

Specification

Quantity

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