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Goat Anti-Neuroligin 3 Antibody

Catalog # Availability Size / Price Inquiry
APR12134G 0.1 mg / $495

Goat Anti-Neuroligin 3 Antibody

Brand

Leading Biology

Catalog Number

APR12134G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Goat Anti-Neuroligin 3 antibody.

Molecular Weight

93895 Da

Cellular Localization

Antigen Cellular Localization: Cell membrane; Single-pass type I membrane protein. Cell junction, synapse. Note=Detected at both glutamatergic and GABAergic synapses.

Host

Goat

Species Reactivity

Human

Isotype

IgG

Symbol

KIAA1480, NL3

GeneID

UniProt ID

Function

Cell surface protein involved in cell-cell-interactions via its interactions with neurexin family members. Plays a role in synapse function and synaptic signal transmission, and may mediate its effects by clustering other synaptic proteins. May promote the initial formation of synapses, but is not essential for this. May also play a role in glia-glia or glia-neuron interactions in the developing peripheral nervous system (By similarity).

Summary

This gene encodes a member of a family of neuronal cell surface proteins. Members of this family may act as splice site-specific ligands for beta-neurexins and may be involved in the formation and remodeling of central nervous system synapses. Mutations in this gene may be associated with autism and Asperger syndrome. Multiple transcript variants encoding distinct isoforms have been identified for this gene.

Form

0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Synonyms

Neuroligin-3, Gliotactin homolog, NLGN3, KIAA1480, NL3

Images

APR12134G (0.1 μg/ml) staining of Human Brain (Amygdala) lysate (35 μg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

HEK293 overexpressing Neuregulin3 (RC207955) and probed with APR12134G (mock transfection in first lane), tested by Origene.

Specification

Quantity

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