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Goat Anti-GRAP Antibody

Catalog # Availability Size / Price Inquiry
APR16286G 0.1 mg / $495

Goat Anti-GRAP Antibody

Brand

Leading Biology

Catalog Number

APR16286G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Goat Anti-GRAP antibody.

Molecular Weight

25337 Da

Host

Goat

Species Reactivity

Human

Isotype

IgG

GeneID

UniProt ID

Function

Couples signals from receptor and cytoplasmic tyrosine kinases to the Ras signaling pathway.

Summary

This gene encodes a member of the GRB2/Sem5/Drk family. This member functions as a cytoplasmic signaling protein which contains an SH2 domain flanked by two SH3 domains. The SH2 domain interacts with ligand-activated receptors for stem cell factor and erythropoietin, and facilitates the formation of a stable complex with the BCR-ABL oncoprotein. This protein also associates with the Ras guanine nucleotide exchange factor SOS1 (son of sevenless homolog 1) through its N-terminal SH3 domain.

Form

0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Synonyms

GRB2-related adapter protein, GRAP

Images

APR16286G (0.3 μg/ml) staining of human thymus lysate (35 μg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Specification

Quantity

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