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Goat Anti-EXOC7 Antibody

Catalog # Availability Size / Price Inquiry
APR16277G 0.1 mg / $495

Goat Anti-EXOC7 Antibody

Brand

Leading Biology

Catalog Number

APR16277G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Goat Anti-EXOC7 antibody.

Molecular Weight

83382 Da

Cellular Localization

Antigen Cellular Localization: Cytoplasm, cytosol. Cell membrane; Peripheral membrane protein Note=Translocates, as a preformed complex with SEC6 and SEC8, to the plasma membrane in response to insulin through the activation of ARHQ.

Host

Goat

Species Reactivity

Human

Isotype

IgG

Symbol

EXO70, KIAA1067

GeneID

UniProt ID

Function

Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. In adipocytes, plays a crucial role in targeting SLC2A4 vesicle to the plasma membrane in response to insulin, perhaps directing the vesicle to the precise site of fusion (By similarity).

Summary

EXOC7 is a component of the exocyst, which is an evolutionarily conserved octameric protein complex essential for exocytosis. The exocyst targets secretory vesicles at specific domains of the plasma membrane for cell surface expansion and protein secretion (Zuo et al., 2006 [PubMed 17086175]).

Form

0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC, E

Synonyms

Exocyst complex component 7, Exocyst complex component Exo70, EXOC7, EXO70, KIAA1067

Images

APR16277G (0.5 μg/ml) staining of Human Lung lysate (35 μg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

APR16277G (0.5 μg/ml) staining of paraffin embedded Human Pancreas. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.

Specification

Quantity

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