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Location: Home > Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > Goat Anti-Aromatase / CYP19A1 Antibody

Goat Anti-Aromatase / CYP19A1 Antibody

Catalog # Availability Size / Price Inquiry
AMM04899G 0.1 mg / $495

Goat Anti-Aromatase / CYP19A1 Antibody

Brand

Leading Biology

Catalog Number

AMM04899G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Goat Anti-Aromatase / CYP19A1 antibody.

Molecular Weight

57883 Da

Cellular Localization

Antigen Cellular Localization: Membrane; Peripheral membrane protein.

Host

Goat

Species Reactivity

Human

Isotype

IgG

Symbol

ARO1, CYAR, CYP19

GeneID

UniProt ID

Function

Catalyzes the formation of aromatic C18 estrogens from C19 androgens.

Summary

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and catalyzes the last steps of estrogen biosynthesis, three successive hydroxylations of the A ring of androgens. Mutations in this gene can result in either increased or decreased aromatase activity; the associated phenotypes suggest that estrogen functions both as a sex steroid hormone and in growth or differentiation. The gene expresses two transcript variants.

Form

0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Synonyms

Aromatase, 1.14.14.14, CYPXIX, Cytochrome P-450AROM, Cytochrome P450 19A1, Estrogen synthase, CYP19A1, ARO1, CYAR, CYP19

Images

AMM04899G (0.1 μg/ml) staining of Human Placenta lysate (35 μg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Specification

Quantity

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