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Goat Anti-APOA4 Antibody

Catalog # Availability Size / Price Inquiry
AMM04884G 0.1 mg / $495

Goat Anti-APOA4 Antibody

Brand

Leading Biology

Catalog Number

AMM04884G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Goat Anti-APOA4 antibody.

Molecular Weight

45399 Da

Cellular Localization

Antigen Cellular Localization: Secreted.

Host

Goat

Species Reactivity

Human

Isotype

IgG

UniProt ID

Function

May have a role in chylomicrons and VLDL secretion and catabolism. Required for efficient activation of lipoprotein lipase by ApoC-II; potent activator of LCAT. Apoa-IV is a major component of HDL and chylomicrons.

Summary

Apoliprotein (apo) A-IV gene contains 3 exons separated by two introns. A sequence polymorphism has been identified in the 3'UTR of the third exon. The primary translation product is a 396-residue preprotein which after proteolytic processing is secreted its primary site of synthesis, the intestine, in association with chylomicron particles. Although its precise function is not known, apo A-IV is a potent activator of lecithin-cholesterol acyltransferase in vitro.

Form

0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC, E

Synonyms

Apolipoprotein A-IV, Apo-AIV, ApoA-IV, Apolipoprotein A4, APOA4

Images

AMM04884G (0.01 μg/ml) staining of Human Duodenum lysate (35 μg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

AMM04884G (2 μg/ml) staining of paraffin embedded Human Intestine. Steamed antigen retrieval with citrate buffer pH 6, HRP-staining.

Specification

Quantity

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