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Goat Anti-ABCD1 Antibody

Catalog # Availability Size / Price Inquiry
AMM04855G 0.1 mg / $495

Goat Anti-ABCD1 Antibody

Brand

Leading Biology

Catalog Number

AMM04855G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Goat Anti-ABCD1 antibody.

Molecular Weight

82937 Da

Cellular Localization

Antigen Cellular Localization: Peroxisome membrane; Multi-pass membrane protein

Host

Goat

Species Reactivity

Human

Isotype

IgG

Symbol

ALD

GeneID

UniProt ID

Function

Probable transporter. The nucleotide-binding fold acts as an ATP-binding subunit with ATPase activity.

Summary

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. This peroxisomal membrane protein is likely involved in the peroxisomal transport or catabolism of very long chain fatty acids. Defects in this gene have been identified as the underlying cause of adrenoleukodystrophy, an X-chromosome recessively inherited demyelinating disorder of the nervous system.

Form

0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Synonyms

ATP-binding cassette sub-family D member 1, Adrenoleukodystrophy protein, ALDP, ABCD1, ALD

Images

HEK293 overexpressing human ABCD1 and probed with AMM04855G at 1ug/ml (mock transfection in first lane).

Specification

Quantity

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