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CRP Antibody

Catalog # Availability Size / Price Inquiry
APG02787G 100 μg / $495

CRP Antibody

Brand

Leading Biology

Catalog Number

APG02787G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CRP antibody.

Molecular Weight

25039 Da

Cellular Localization

Antigen Cellular Localization: Secreted.

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Target

CRP

Isotype

Rabbit IgG

Symbol

PTX1

GeneID

UniProt ID

Function

Displays several functions associated with host defense: it promotes agglutination, bacterial capsular swelling, phagocytosis and complement fixation through its calcium-dependent binding to phosphorylcholine. Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells.

Summary

C-Reactive protein (CRP) is an acute-phase protein that can have both pro-and anti-inflammatory effects. CRP is synthesized by the liver in response to factors released by fat cells or adipocytes. CRP is a member of the pentaxin family of proteins and in its native form is composed of five identical subunits, non-covalently linked to form a symmetrical disc of ~ 115 KDa. Widely used as a clinical marker of the state of inflammation. Increased CRP levels are found in inflammatory conditions including: bacterial infection, rheumatic fever, active arthritis, myocardial infarction, malignancies and in the post-operative state.

Form

Liquid

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB

Synonyms

C-Reactive Protein

Images

Western blot with CRP antibody: Lane 1: 60 μg Jurkat cell lysate; Lane 2: 44 μg mouse muscle lysate; Lane 3: 60 μg rat kidney lysate; Lane 4: 2 ng Recombinant human CRP; Lane 5: 10 ng Recombinant human CRP

Specification

Quantity

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