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Insulin Antibody

Catalog # Availability Size / Price Inquiry
APR08003G 100 μg / $495

Insulin Antibody

Brand

Leading Biology

Catalog Number

APR08003G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Insulin antibody.

Molecular Weight

11981 Da

Cellular Localization

Antigen Cellular Localization: Secreted.

Host

Rabbit

Species Reactivity

Human

Target

Insulin

Isotype

Rabbit IgG

GeneID

UniProt ID

Function

Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.

Summary

Insulin is important in stimulating the uptake of glucose from blood in the skeletal muscle and adipose tissue. It is secrered by pancreatic β cells thro μgh a glucose sensing pathway. Insulin also increases cell permeability to monosaccharides, amino acids and fatty acids. Insulin is first formed as a precursor molecule, preproinsulin which is then processed into proinsulin and finally to the mature insulin hormone. A mature form of insulin has an A chain and a B chain that are connnected by two dilsufide bonds. Defects in insulin are the cause of type-II diabetes mellitus.

Form

Liquid

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB

Synonyms

Insulin A chain, Insulin B chain, Proinsulin

Images

Western blot analysis using recombinant human Insulin.

Specification

Quantity

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