> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > PlGF-1 AntibodyBrand |
Leading Biology | Catalog Number |
AMR09383G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality PlGF-1 antibody.
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Molecular Weight |
24789 Da
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Cellular Localization |
Antigen Cellular Localization:
Secreted. Note=The three isoforms are secreted but PlGF-2 appears to remain cell attached unless released by heparin
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Host |
Rabbit
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Species Reactivity |
Human
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Target |
PIGF
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Isotype |
Rabbit IgG
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Symbol |
PGFL, PLGF
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GeneID |
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UniProt ID |
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Function |
Growth factor active in angiogenesis and endothelial cell growth, stimulating their proliferation and migration. It binds to the receptor FLT1/VEGFR-1. Isoform PlGF-2 binds NRP1/neuropilin-1 and NRP2/neuropilin-2 in a heparin-dependent manner. Also promotes cell tumor growth.
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Summary |
PlGF-1(also called Placenta Growth Factor-1, PLGF, and PGF) is an angiogenic factor that belongs to the cysteine-knot superfamily of growth factors. PlGF-1 is expressed in placental tissues, colon and mammary carcinomas. It signals thro μgh the VEGFR-1/FLT1 receptor and stimulates endothelial cell proliferation and migration. Human PlGF-1 is a 29.7 kDa disulfide-linked homodimeric protein of two 131 amino acid polypeptide chains.
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Form |
Liquid |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB
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Synonyms |
PIGF1, PIGF 1, PIGF-1, Phosphatidylinositol glycan biosynthesis class F, PIG F
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Images |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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