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HMG-CoA Reductase Antibody

Catalog # Availability Size / Price Inquiry
APR07768G 100 μg / $495

HMG-CoA Reductase Antibody

Brand

Leading Biology

Catalog Number

APR07768G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality HMG-CoA Reductase antibody.

Molecular Weight

97476 Da

Cellular Localization

Antigen Cellular Localization: Endoplasmic reticulum membrane; Multi-pass membrane protein

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Target

AMPK?1

Isotype

Rabbit IgG

GeneID

UniProt ID

Function

Transmembrane glycoprotein that is the rate-limiting enzyme in cholesterol biosynthesis as well as in the biosynthesis of nonsterol isoprenoids that are essential for normal cell function including ubiquinone and geranylgeranyl proteins.

Summary

HMG-CoA reductase (HMGCR) is the rate-limiting enzyme for cholesterol biosynthesis. HMGCR is regulated via a negative feedback mechanism mediated by sterols and non-sterol metabolites derived from the product of the reductase reaction. Statin, a class of cholesterol-lowering dr μgs inhibits HMGCR by lowering plasma cholesterol.

Form

Liquid

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB

Synonyms

hydroxymethylglutaryl-CoA reductase

Images

Specification

Quantity

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