> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > SERPINA1 antibody - C-terminal regionBrand |
Leading Biology | Catalog Number |
AMR09902G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality SERPINA1 antibody - C-terminal region.
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Molecular Weight |
46kDa
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Cellular Localization |
Antigen Cellular Localization:
Secreted. Endoplasmic reticulum. Note=The S and Z allele are not secreted effectively and accumulate intracellularly in the endoplasmic reticulum
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Host |
Rabbit
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Species Reactivity |
Human
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Symbol |
AAT, PI
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GeneID |
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UniProt ID |
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Function |
Inhibitor of serine proteases. Its primary target is elastase, but it also has a moderate affinity for plasmin and thrombin. Irreversibly inhibits trypsin, chymotrypsin and plasminogen activator. The aberrant form inhibits insulin-induced NO synthesis in platelets, decreases coagulation time and has proteolytic activity against insulin and plasmin.
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Summary |
Inhibitor of serine proteases. Its primary target is elastase, but it also has a moderate affinity for plasmin and thrombin. Irreversibly inhibits trypsin, chymotrypsin and plasminogen activator. The aberrant form inhibits insulin-induced NO synthesis in platelets, decreases coagulation time and has proteolytic activity against insulin and plasmin.
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Form |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, IHC
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Synonyms |
Alpha-1-antitrypsin, Alpha-1 protease inhibitor, Alpha-1-antiproteinase, Serpin A1, Short peptide from AAT, SPAAT, SERPINA1, AAT, PI
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Images |
WB Suggested Anti-SERPINA1 Antibody Titration: 4.0-8.0 Positive Control: Human kidney lysate
WB Suggested Anti-SERPINA1 Antibody Titration: 1.25μg/ml ELISA Titer: 1:12500 Positive Control: HepG2 cell lysate SERPINA1 is strongly supported by BioGPS gene expression data to be expressed in Human HepG2 cells |
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Specification |
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Quantity |
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Tel: 1-661-524(LBI)-0262
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