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Location: Home > Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > SERPINA1 antibody - C-terminal region

SERPINA1 antibody - C-terminal region

Catalog # Availability Size / Price Inquiry
AMR09902G 100 μg / $495

SERPINA1 antibody - C-terminal region

Brand

Leading Biology

Catalog Number

AMR09902G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality SERPINA1 antibody - C-terminal region.

Molecular Weight

46kDa

Cellular Localization

Antigen Cellular Localization: Secreted. Endoplasmic reticulum. Note=The S and Z allele are not secreted effectively and accumulate intracellularly in the endoplasmic reticulum

Host

Rabbit

Species Reactivity

Human

Symbol

AAT, PI

GeneID

UniProt ID

Function

Inhibitor of serine proteases. Its primary target is elastase, but it also has a moderate affinity for plasmin and thrombin. Irreversibly inhibits trypsin, chymotrypsin and plasminogen activator. The aberrant form inhibits insulin-induced NO synthesis in platelets, decreases coagulation time and has proteolytic activity against insulin and plasmin.

Summary

Inhibitor of serine proteases. Its primary target is elastase, but it also has a moderate affinity for plasmin and thrombin. Irreversibly inhibits trypsin, chymotrypsin and plasminogen activator. The aberrant form inhibits insulin-induced NO synthesis in platelets, decreases coagulation time and has proteolytic activity against insulin and plasmin.

Form

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC

Synonyms

Alpha-1-antitrypsin, Alpha-1 protease inhibitor, Alpha-1-antiproteinase, Serpin A1, Short peptide from AAT, SPAAT, SERPINA1, AAT, PI

Images

WB Suggested Anti-SERPINA1 Antibody Titration: 4.0-8.0 Positive Control: Human kidney lysate

WB Suggested Anti-SERPINA1 Antibody Titration: 1.25μg/ml ELISA Titer: 1:12500 Positive Control: HepG2 cell lysate SERPINA1 is strongly supported by BioGPS gene expression data to be expressed in Human HepG2 cells

Specification

Quantity

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