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Location: Home > Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > Aldolase A (ALDOA) Antibody (CT)

Aldolase A (ALDOA) Antibody (CT)

Catalog # Availability Size / Price Inquiry
APG01810G 100 μl / $495

Aldolase A (ALDOA) Antibody (CT)

Brand

Leading Biology

Catalog Number

APG01810G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Aldolase A (ALDOA) antibody (CT).

Molecular Weight

39420 Da

Cellular Localization

Antigen Cellular Localization: Cytoplasm, myofibril, sarcomere, I band. Cytoplasm, myofibril, sarcomere, M line. Note=In skeletal muscle, accumulates around the M line and within the I band, colocalizing with FBP2 on both sides of the Z line in the absence of Ca(2+)

Host

Rabbit

Species Reactivity

Human, Mouse, Rabbit

Target

ALDOA

Isotype

Rabbit IgG

Symbol

ALDA

GeneID

UniProt ID

Function

Plays a key role in glycolysis and gluconeogenesis. In addition, may also function as scaffolding protein (By similarity).

Summary

Fructose bisphosphate aldolase A, also known as Aldolase A is a glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. It is found in the developing embryo and is produced in even greater amounts in adult muscle. Aldolase A expression is repressed in adult liver, kidney and intestine and similar to aldolase C levels in brain and other nervous tissue. Deficiency has been associated with myopathy and hemolytic anemia. Recombinant human Aldolase A, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Form

Liquid. In PBS containing 0.02% sodium azide.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC

Synonyms

ALDOA; ALDA; Fructose-bisphosphate aldolase A; Lung cancer antigen NY-LU-1; Muscle-type aldolase.

Images

Western blot analysis of mouse liver tissue lysates (35 μg lysate).

Formalin-fixed and paraffin-embedded human lung carcinoma reacted with ALDOA antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.

Specification

Quantity

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