> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > Galectin-3 AntibodyBrand |
Leading Biology | Catalog Number |
AMM05899G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Galectin-3 antibody.
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Molecular Weight |
26152 Da
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Cellular Localization |
Antigen Cellular Localization:
Cytoplasm. Nucleus. Secreted. Note=Secreted by a non-classical secretory pathway and associates with the cell surface
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Host |
Rabbit
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Species Reactivity |
Human
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Target |
Galectin 3
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Isotype |
Rabbit IgG
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Symbol |
MAC2
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GeneID |
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UniProt ID |
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Function |
Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis (By similarity). In the nucleus: acts as a pre-mRNA splicing factor. Involved in acute inflammatory responses including neutrophil activation and adhesion, chemoattraction of monocytes macrophages, opsonization of apoptotic neutrophils, and activation of mast cells.
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Summary |
Galectins are a family of soluble β-galactoside-binding animal lectins that modulate cell-to-cell and cell-to-ECM interactions, as well as apoptosis. Galectin-3 encodes a 30-35 kDa protein containing a single carbohydrate binding domain, which binds galactose-containing glycoconj μgates. Upregulated expression of Galectin-3 is involved in cancer progression and metastasis.
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Form |
Liquid |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB
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Synonyms |
Galectin3, Galectin 3, Galectin-3, Galactoside binding protein, GALBP, GAL3 , GAL 3, GAL-3, Galactose-specific lectin 3, Laminin-binding protein, MAC 2 antigen, MAC2, Lectin L-29, L-34 galactoside-binding lectin
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Images |
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Specification |
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Quantity |
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| 6 | Leading Biology | APR03502G | IGHG1 Antibody (Center) | 100 μl | Polyclonal Antibodies |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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