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CGI-58 Antibody

Catalog # Availability Size / Price Inquiry
APG02565G 100 μg / $495

CGI-58 Antibody

Brand

Leading Biology

Catalog Number

APG02565G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CGI-58 antibody.

Molecular Weight

39096 Da

Cellular Localization

Antigen Cellular Localization: Cytoplasm. Lipid droplet. Note=Colocalized with PLIN and ADRP on the surface of lipid droplets. The localization is dependent upon the metabolic status of the adipocytes and the activity of PKA (By similarity).

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Target

CGI-58

Isotype

Rabbit IgG

Symbol

NCIE2

GeneID

UniProt ID

Function

Lysophosphatidic acid acyltransferase which functions in phosphatidic acid biosynthesis. May regulate the cellular storage of triacylglycerol through activation of the phospholipase PNPLA2. Involved in keratinocyte differentiation.

Summary

Comparative Gene Identification-58 (CGI-58) is a causal gene of Dorfman-Chanarin syndrome, a neutral lipid storage disease characterized by the presence of intracellular lipid droplets in tissues. CGI-58 comes from a large family of proteins characterized by an α/β hydrolase fold that activates adipose triglyceride lipase thus, may involve in lipid metabolism.

Form

Liquid

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB

Synonyms

Comparative Gene Identification-58, CGI58, CGI-58, CGI 58

Images

Western blot analysis of CGI-58 expression in 3T3 cell lysate.

Specification

Quantity

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