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SLK Antibody

Catalog # Availability Size / Price Inquiry
APR13402G 100 μl / $495

SLK Antibody

Brand

Leading Biology

Catalog Number

APR13402G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality SLK antibody.

Molecular Weight

142695 Da

Cellular Localization

Antigen Cellular Localization: Cytoplasm.

Host

Rabbit

Species Reactivity

Human, Mouse

Target

SLK

Isotype

Rabbit IgG

Symbol

KIAA0204, STK2

GeneID

UniProt ID

Function

Mediates apoptosis and actin stress fiber dissolution.

Summary

SLK (STE20-like kinase), also known as STK2 (serine/threonine protein kinase 2) or se20-9, is a member of the serine/threonine kinase subfamily, Ste20. This subfamily is comprised of several mammalian kinases which exhibit sequence similarity to the Saccharomyces cerevisiae serine/threonine kinase Ste20, a protein involved in relaying signals from G protein-coupled receptors to cytosolic MAP kinase cascades. Members of this subfamily include KHS, GLK, YSK1, HPK1, Krs-1, Krs-2, GC kinase, HGK and SLK. SLK is a ubiquitously expressed protein that localizes to the cytoplasm and contains an N-terminal protein kinase domain, a central coiled-coil domain and a C-terminal ATH domain. SLK is activated through cleavage by caspase-3. SLK indirectly associates with microtubules and plays an important role in cellular stress, cell motility, cell death and cytoskeletal dynamics.

Form

Liquid. In PBS containing 0.02% sodium azide.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IP

Synonyms

SLK, STE20-like Kinase, SLK, Sucrose nonfermenting like kinase, STK2, Serine/Threonine Kinase 2

Images

Specification

Quantity

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