> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > EMR2 AntibodyBrand |
Leading Biology | Catalog Number |
APR15824G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality EMR2 antibody.
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Molecular Weight |
90472 Da
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Cellular Localization |
Antigen Cellular Localization:
Cell membrane; Multi-pass membrane protein. Cell projection, ruffle membrane; Multi-pass membrane protein Note=Localized at the leading edge of migrating cells
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Host |
Rabbit
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Species Reactivity |
Human
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Target |
EMR2
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Isotype |
Rabbit IgG
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GeneID |
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UniProt ID |
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Function |
Cell surface receptor that binds to the chondroitin sulfate moiety of glycosaminoglycan chains and promotes cell attachment. Promotes granulocyte chemotaxis, degranulation and adhesion. In macrophages, promotes the release of inflammatory cytokines, including IL8 and TNF.
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Summary |
EGF-like module-containing mucin-like receptor 2 (EMR2) is a member of the class B seven-span transmembrane (TM7) receptor family. EMR2 is expressed predominantly by cells of the immune system such as leukocytes. EMR2 is proteo-lytically cleaved into two subunits: a seven-transmembrane subunit, and an extracellular α subunit.
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Form |
Liquid |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB
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Synonyms |
EGF-like module receptor 2, CD312
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Images |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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