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Cytochrome P450 Antibody

Catalog # Availability Size / Price Inquiry
APR07490G 100 μg / $495

Cytochrome P450 Antibody

Brand

Leading Biology

Catalog Number

APR07490G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Cytochrome P450 antibody.

Molecular Weight

56849 Da

Cellular Localization

Antigen Cellular Localization: Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein

Host

Rabbit

Species Reactivity

Human, Mouse, Rat, Dog

Target

Cytochrome p450

Isotype

Rabbit IgG

Symbol

CYP2E

GeneID

UniProt ID

Function

Metabolizes several precarcinogens, drugs, and solvents to reactive metabolites. Inactivates a number of drugs and xenobiotics and also bioactivates many xenobiotic substrates to their hepatotoxic or carcinogenic forms.

Summary

Cytochrome P450 is mainly found in liver, and can metabolize a wide range of compounds such as organic solvents, acetaminophen, dimethylnitrosoamine and aliphatic alcohol, which have certain toxicological effects in humans. Ethanol-induced cytochrome P450 IIE1 is considered to be one of the major causes of oxidative stress in the liver following ethanol treatment.

Form

Liquid

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB

Synonyms

AHH , AHRR, CYP1A1 , CP11 , CYP1, P1-450, CYPIA1, P450-C, , P450DX, P450-P1

Images

Western blot analysis of cytochrome P450 using Rat kidney tissue lysate.

Specification

Quantity

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