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OTC Antibody (Center)

Catalog # Availability Size / Price Inquiry
APR08891G 100 μl / $495

OTC Antibody (Center)

Brand

Leading Biology

Catalog Number

APR08891G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality OTC antibody (Center).

Molecular Weight

39935 Da

Cellular Localization

Antigen Cellular Localization: Mitochondrion matrix.

Host

Rabbit

Species Reactivity

Human

Immunogen

71-98 aa

Target

This OTC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 71-98 amino acids from the Central region of human OTC.

Isotype

Rabbit Ig

GeneID

UniProt ID

Summary

OTC is a mitochondrial matrix enzyme. Missense, nonsense, and frameshift mutations in this enzyme lead to ornithine transcarbamylase deficiency, which causes hyperammonemia.

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, FC, IHC-P, E

Dilution

WB~~1:1000 IHC-P~~1:10~50 FC~~1:10~50

Synonyms

Ornithine carbamoyltransferase, mitochondrial, Ornithine transcarbamylase, OTCase, OTC

Images

Anti-OTC Antibody (Center) at 1:1000 dilution + human liver lysate Lysates/proteins at 20 μg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 40 kDa Blocking/Dilution buffer: 5% NFDM/TBST.

OTC Antibody (Center) (Cat. APR08891G) western blot analysis in SW620 cell line and mouse liver,rat liver lysates (35ug/lane).This demonstrates the OTC antibody detected the OTC protein (arrow).

Formalin-fixed and paraffin-embedded human hepatoarcinoma with OTC Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

Specification

Quantity

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