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PRLR Antibody (Center)

Catalog # Availability Size / Price Inquiry
AMR09546G 100 μl / $495

PRLR Antibody (Center)

Brand

Leading Biology

Catalog Number

AMR09546G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality PRLR antibody (Center).

Molecular Weight

69506 Da

Cellular Localization

Antigen Cellular Localization: Membrane; Single-pass type I membrane protein

Host

Rabbit

Species Reactivity

Human

Immunogen

147-179 aa

Target

This PRLR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 147-179 amino acids from the Central region of human PRLR.

Isotype

Rabbit Ig

GeneID

UniProt ID

Function

This is a receptor for the anterior pituitary hormone prolactin (PRL). Acts as a prosurvival factor for spermatozoa by inhibiting sperm capacitation through suppression of SRC kinase activation and stimulation of AKT. Isoform 4 is unable to transduce prolactin signaling. Isoform 6 is unable to transduce prolactin signaling.

Summary

This is a receptor for the anterior pituitary hormone prolactin (PRL). Isoform 4 is unable to transduce prolactin signaling. Isoform 6 is unable to transduce prolactin signaling.

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Dilution

WB~~1:1000

Synonyms

Prolactin receptor, PRL-R, PRLR

Images

PRLR Antibody (Center) (Cat. AMR09546G) western blot analysis in MCF-7 cell line and human placenta tissue lysates (35ug/lane).This demonstrates the PRLR antibody detected the PRLR protein (arrow).

Specification

Quantity

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