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ECE2 Antibody (Center)

Catalog # Availability Size / Price Inquiry
AMM05862G 100 μl / $495

ECE2 Antibody (Center)

Brand

Leading Biology

Catalog Number

AMM05862G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality ECE2 antibody (Center).

Molecular Weight

99773 Da

Cellular Localization

Antigen Cellular Localization: Golgi apparatus membrane; Single-pass type II membrane protein. Cytoplasmic granule membrane; Single-pass type II membrane protein

Host

Rabbit

Species Reactivity

Human

Immunogen

551-579 aa

Target

This ECE2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 551-579 amino acids from the Central region of human ECE2.

Isotype

Rabbit Ig

Symbol

KIAA0604

GeneID

UniProt ID

Function

Converts big endothelin-1 to endothelin-1. Also involved in the processing of various neuroendocrine peptides, including neurotensin, angiotensin I, substance P, proenkephalin-derived peptides, and prodynorphin-derived peptides. May limit beta- amyloid peptide accumulation in brain. May also have methyltransferase activity.

Summary

Converts big endothelin-1 to endothelin-1. Also involved in the processing of various neuroendocrine peptides, including neurotensin, angiotensin I, substance P, proenkephalin-derived peptides, and prodynorphin-derived peptides. May limit beta-amyloid peptide accumulation in brain. May also have methyltransferase activity.

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, E

Dilution

IHC-P~~1:25 WB~~1:1000

Synonyms

Endothelin-converting enzyme 2, ECE-2, Methyltransferase-like region, 211-, Endothelin-converting enzyme 2 region, ECE2, KIAA0604

Images

Immunohistochemical analysis of paraffin-embedded H. prostate section using ECE2 Antibody (Center)( AP20460C). AP20460C was diluted at 1:25 dilution. A undiluted biotinylated goat polyvalent antibody was used as the secondary, followed by DAB staining.

ECE2 Antibody (Center) (Cat. AMM05862G) western blot analysis in U251 cell line lysates (35ug/lane).This demonstrates the ECE2 antibody detected the ECE2 protein (arrow).

Specification

Quantity

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