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CGB/HCG-Beta Antibody (C-term)

Catalog # Availability Size / Price Inquiry
APG02564G 100 μl / $495

CGB/HCG-Beta Antibody (C-term)

Brand

Leading Biology

Catalog Number

APG02564G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CGB/HCG-Beta antibody (C-term).

Molecular Weight

17739 Da

Cellular Localization

Antigen Cellular Localization: Secreted.

Host

Rabbit

Species Reactivity

Human

Immunogen

137-165 aa

Target

This CGB/HCG-Beta antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 137-165 amino acids from the C-terminal region of human CGB/HCG-Beta.

Isotype

Rabbit Ig

Symbol

CGB3

GeneID

UniProt ID

Function

Stimulates the ovaries to synthesize the steroids that are essential for the maintenance of pregnancy.

Summary

This gene is a member of the glycoprotein hormone beta chain family and encodes the beta 3 subunit of chorionic gonadotropin (CG). Glycoprotein hormones are heterodimers consisting of a common alpha subunit and an unique beta subunit which confers biological specificity. CG is produced by the trophoblastic cells of the placenta and stimulates the ovaries to synthesize the steroids that are essential for the maintenance of pregnancy. The beta subunit of CG is encoded by 6 genes which are arranged in tandem and inverted pairs on chromosome 19q13.3 and contiguous with the luteinizing hormone beta subunit gene.

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, E

Dilution

WB~~1:1000 IHC-P~~1:10~50

Synonyms

Choriogonadotropin subunit beta, CG-beta, Chorionic gonadotrophin chain beta, CGB, CGB3

Images

Anti-CGB/ HCG-Beta Antibody (C-term)at 1:2000 dilution + human placenta lysates Lysates/proteins at 20 μg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution Predicted band size : 18 kDa Blocking/Dilution buffer: 5% NFDM/TBST.

CGB/HCG-Beta Antibody (C-term) (Cat. APG02564G) western blot analysis in human placenta tissue lysates (35ug/lane).This demonstrates the CGB/HCG-Beta antibody detected the CGB/HCG-Beta protein (arrow).

CGB/HCG-Beta Antibody (C-term) (Cat. APG02564G)immunohistochemistry analysis in formalin fixed and paraffin embedded human placenta tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of CGB/HCG-Beta Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.

Specification

Quantity

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