> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > UGT8 antibody (Center)Brand |
Leading Biology | Catalog Number |
APR07201G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality UGT8 antibody (Center).
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Molecular Weight |
61438 Da
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Cellular Localization |
Antigen Cellular Localization:
Membrane; Single-pass membrane protein
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Host |
Rabbit
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Species Reactivity |
Human, Mouse
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Immunogen |
366-393 aa
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Target |
This UGT8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 366-393 amino acids from the Central region of human UGT8.
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Isotype |
Rabbit Ig
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Symbol |
CGT, UGT4
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GeneID |
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UniProt ID |
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Function |
Catalyzes the transfer of galactose to ceramide, a key enzymatic step in the biosynthesis of galactocerebrosides, which are abundant sphingolipids of the myelin membrane of the central nervous system and peripheral nervous system.
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Summary |
Galactocerebrosides are abundant sphingolipids of themyelin membrane of the central nervous system and peripheralnervous system and are also present in small amounts in kidney. Thekey enzymatic step in the biosynthesis of galactocerebrosidesconsists of the transfer of galactose to ceramide catalyzed byUDP-galactose ceramide galactosyltransferase (CGT, EC 2.4.1.45).The enzyme encoded by the CGT gene is the first involved in complexlipid biosynthesis in the myelinating oligodendrocyte.[supplied byOMIM].
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Form |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, IHC-P, E
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Dilution |
WB~~1:1000
IHC-P~~1:10~50
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Synonyms |
2-hydroxyacylsphingosine 1-beta-galactosyltransferase, Ceramide UDP-galactosyltransferase, Cerebroside synthase, UDP-galactose-ceramide galactosyltransferase, UGT8, CGT, UGT4
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Images |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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