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ATG13 Antibody (N-term)

Catalog # Availability Size / Price Inquiry
APG02023G 100 μl / $495

ATG13 Antibody (N-term)

Brand

Leading Biology

Catalog Number

APG02023G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality ATG13 antibody (N-term).

Molecular Weight

56572 Da

Cellular Localization

Antigen Cellular Localization: Cytoplasm, cytosol. Preautophagosomal structure. Note=Under starvation conditions, is localized to puncate structures primarily representing the isolation membrane; the isolation membrane sequesters a portion of the cytoplasm resulting in autophagosome formation.

Host

Rabbit

Species Reactivity

Human

Immunogen

1-30 aa

Target

This ATG13 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human ATG13.

Isotype

Rabbit Ig

Symbol

KIAA0652

GeneID

UniProt ID

Function

Autophagy factor required for autophagosome formation and mitophagy. Target of the TOR kinase signaling pathway that regulates autophagy through the control of the phosphorylation status of ATG13 and ULK1, and the regulation of the ATG13-ULK1- RB1CC1 complex. Through its regulation of ULK1 activity, plays a role in the regulation of the kinase activity of mTORC1 and cell proliferation.

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, E

Dilution

WB~~1:1000 IHC-P~~1:50~100

Synonyms

Autophagy-related protein 13, ATG13, KIAA0652

Images

ATG13 Antibody (N-term) (Cat. APG02023G) western blot analysis in MDA-MB435,CEM,T47D cell line and mouse cerebellum tissue lysates (35ug/lane).This demonstrates the ATG13 antibody detected the ATG13 protein (arrow).

ATG13 Antibody (N-term) (Cat. APG02023G) immunohistochemistry analysis in formalin fixed and paraffin embedded human lung carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the ATG13 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.

Specification

Quantity

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