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PLA1A Antibody (Center)

Catalog # Availability Size / Price Inquiry
AMR09314G 100 μl / $495

PLA1A Antibody (Center)

Brand

Leading Biology

Catalog Number

AMR09314G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality PLA1A antibody (Center).

Molecular Weight

49715 Da

Cellular Localization

Antigen Cellular Localization: Secreted.

Host

Rabbit

Species Reactivity

Human, Mouse

Immunogen

329-358 aa

Target

This PLA1A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 329-358 amino acids from the Central region of human PLA1A.

Isotype

Rabbit Ig

Symbol

NMD, PSPLA1

GeneID

UniProt ID

Function

Hydrolyzes the ester bond at the sn-1 position of glycerophospholipids and produces 2-acyl lysophospholipids. Hydrolyzes phosphatidylserine (PS) in the form of liposomes and 1- acyl-2 lysophosphatidylserine (lyso-PS), but not triolein, phosphatidylcholine (PC), phosphatidylethanolamine (PE), phosphatidic acid (PA) or phosphatidylinositol (PI). Isoform 2 hydrolyzes lyso-PS but not PS. Hydrolysis of lyso-PS in peritoneal mast cells activated by receptors for IgE leads to stimulate histamine production.

Summary

Phosphatidylserine-specific phospholipase A1-alpha (PLA1A) acts specifically on phosphatidylserine (PS) and 1-acyl-2-lysophosphatidylserine (lyso-PS) to hydrolyze fatty acids at the sn-1 position of these phospholipids.

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Dilution

WB~~1:1000

Synonyms

Phospholipase A1 member A, 311-, Phosphatidylserine-specific phospholipase A1, PS-PLA1, PLA1A, NMD, PSPLA1

Images

PLA1A Antibody (Center) (Cat. AMR09314G) western blot analysis in mouse liver tissue and CEM cell line lysates (35ug/lane).This demonstrates the PLA1A antibody detected the PLA1A protein (arrow).

Specification

Quantity

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