> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > ORAI1 Antibody (Center)Brand |
Leading Biology | Catalog Number |
APR17666G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality ORAI1 antibody (Center).
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Molecular Weight |
32668 Da
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Cellular Localization |
Antigen Cellular Localization:
Cell membrane; Multi- pass membrane protein Note=Isoform beta is more mobile in the plasma membrane
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Host |
Rabbit
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Species Reactivity |
Human, Mouse
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Immunogen |
145-173 aa
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Target |
This ORAI1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 145-173 amino acids from the Central region of human ORAI1.
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Isotype |
Rabbit Ig
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Symbol |
CRACM1, TMEM142A
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GeneID |
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UniProt ID |
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Function |
Ca(2+) release-activated Ca(2+) (CRAC) channel subunit which mediates Ca(2+) influx following depletion of intracellular Ca(2+) stores and channel activation by the Ca(2+) sensor, STIM1. CRAC channels are the main pathway for Ca(2+) influx in T-cells and promote the immune response to pathogens by activating the transcription factor NFAT.
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Summary |
ORAI1 is a plasma membrane protein essential for store-operated calcium entry.
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Form |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, IHC-P, E
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Dilution |
WB~~1:2000
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Synonyms |
Calcium release-activated calcium channel protein 1, Protein orai-1, Transmembrane protein 142A, ORAI1, CRACM1, TMEM142A
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Images |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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