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YWHAZ Antibody (T232)

Catalog # Availability Size / Price Inquiry
APR14007G 100 μl / $495

YWHAZ Antibody (T232)

Brand

Leading Biology

Catalog Number

APR14007G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality YWHAZ antibody (T232).

Molecular Weight

27745 Da

Cellular Localization

Antigen Cellular Localization: Cytoplasm. Melanosome. Note=Located to stage I to stage IV melanosomes

Host

Rabbit

Species Reactivity

Human

Immunogen

211-239 aa

Target

This YWHAZ antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 211-239 amino acids from human YWHAZ.

Isotype

Rabbit Ig

GeneID

UniProt ID

Function

Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner.

Summary

14-3-3 protein zeta/delta belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This protein interacts with IRS1 protein, suggesting a role in regulating insulin sensitivity. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and sheep orthologs.

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

IHC-P, WB, E

Dilution

WB~~1:1000 IHC-P~~1:10~50

Synonyms

14-3-3 protein zeta/delta, Protein kinase C inhibitor protein 1, KCIP-1, YWHAZ

Images

Western blot analysis of anti-14-3-3 protein zeta/delta Anbtibody (T232)(Cat. APR14007G) in A375 cell line lysates (35ug/lane). 14-3-3 (arrow) was detected using the purified Pab.

Formalin-fixed and paraffin-embedded human testis tissue reacted with YWHAZ Antibody (Cat. APR14007G), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

Specification

Quantity

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