> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > YWHAZ Antibody (T232)Brand |
Leading Biology | Catalog Number |
APR14007G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality YWHAZ antibody (T232).
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Molecular Weight |
27745 Da
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Cellular Localization |
Antigen Cellular Localization:
Cytoplasm. Melanosome. Note=Located to stage I to stage IV melanosomes
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Host |
Rabbit
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Species Reactivity |
Human
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Immunogen |
211-239 aa
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Target |
This YWHAZ antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 211-239 amino acids from human YWHAZ.
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Isotype |
Rabbit Ig
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GeneID |
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UniProt ID |
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Function |
Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner.
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Summary |
14-3-3 protein zeta/delta belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This protein interacts with IRS1 protein, suggesting a role in regulating insulin sensitivity. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and sheep orthologs.
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Form |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
IHC-P, WB, E
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Dilution |
WB~~1:1000
IHC-P~~1:10~50
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Synonyms |
14-3-3 protein zeta/delta, Protein kinase C inhibitor protein 1, KCIP-1, YWHAZ
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Images |
Western blot analysis of anti-14-3-3 protein zeta/delta Anbtibody (T232)(Cat. APR14007G) in A375 cell line lysates (35ug/lane). 14-3-3 (arrow) was detected using the purified Pab.
Formalin-fixed and paraffin-embedded human testis tissue reacted with YWHAZ Antibody (Cat. APR14007G), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. |
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Specification |
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Quantity |
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Tel: 1-661-524(LBI)-0262
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