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Location: Home > Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > CYP4A11 (4A22) Antibody (C-term)

CYP4A11 (4A22) Antibody (C-term)

Catalog # Availability Size / Price Inquiry
APG02896G 100 μl / $495

CYP4A11 (4A22) Antibody (C-term)

Brand

Leading Biology

Catalog Number

APG02896G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CYP4A11 (4A22) antibody (C-term).

Molecular Weight

59348 Da

Cellular Localization

Antigen Cellular Localization: Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein

Host

Rabbit

Species Reactivity

Human

Immunogen

407-435 aa

Target

This CYP4A11 (4A22) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 407-435 amino acids from the C-terminal region of human CYP4A11 (4A22).

Isotype

Rabbit Ig

Symbol

CYP4A2

GeneID

UniProt ID

Function

Catalyzes the omega- and (omega-1)-hydroxylation of various fatty acids such as laurate, myristate and palmitate. Has little activity toward prostaglandins A1 and E1. Oxidizes arachidonic acid to 20-hydroxyeicosatetraenoic acid (20-HETE).

Summary

CYP4A11 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and hydroxylates medium-chain fatty acids such as laurate and myristate.

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IF, E

Dilution

WB~~1:1000 IF~~1:10~50

Synonyms

Cytochrome P450 4A11, 20-hydroxyeicosatetraenoic acid synthase, 20-HETE synthase, CYP4AII, CYPIVA11, Cytochrome P-450HK-omega, Cytochrome P450HL-omega, Fatty acid omega-hydroxylase, Lauric acid omega-hydroxylase, CYP4A11, CYP4A2

Images

Western blot analysis of anti-CYP4A11 (4A22) Antibody (C-term) (Cat. APG02896G) in NCI-H460 cell line lysates (35ug/lane).CYP4A11(arrow) was detected using the purified Pab.

Confocal immunofluorescent analysis of CYP4A11 (4A22) Antibody (C-term)( APG02896G) with NCI-H460 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green).DAPI was used to stain the cell nuclear (blue).

Specification

Quantity

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