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TNK1 Antibody

Catalog # Availability Size / Price Inquiry
AMM08259G 100 μl / $495

TNK1 Antibody

Brand

Leading Biology

Catalog Number

AMM08259G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality TNK1 antibody.

Molecular Weight

72468 Da

Cellular Localization

Antigen Cellular Localization: Cytoplasm. Membrane; Peripheral membrane protein

Host

Rabbit

Species Reactivity

Human

Target

This TNK1 antibody is generated from rabbits immunized with TNK1 recombinant protein.

Isotype

Rabbit Ig

GeneID

UniProt ID

Function

Involved in negative regulation of cell growth. Has tumor suppressor properties. Plays a negative regulatory role in the Ras-MAPK pathway. May function in signaling pathways utilized broadly during fetal development and more selectively in adult tissues and in cells of the lymphohematopoietic system. Could specifically be involved in phospholipid signal transduction.

Summary

Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains.

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Dilution

WB~~1:1000

Synonyms

Non-receptor tyrosine-protein kinase TNK1, CD38 negative kinase 1, TNK1 {ECO:0000312|EMBL:AAC994121}

Images

Western blot analysis of TNK1 Antibody (Cat. AMM08259G) in T47D cell line lysates (35ug/lane). TNK1 (arrow) was detected using the purified Pab.

Specification

Quantity

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