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SOD2 Antibody

Catalog # Availability Size / Price Inquiry
APR07183G 100 μl / $495

SOD2 Antibody

Brand

Leading Biology

Catalog Number

APR07183G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality SOD2 antibody.

Molecular Weight

24722 Da

Cellular Localization

Antigen Cellular Localization: Mitochondrion matrix.

Host

Rabbit

Species Reactivity

Human

Target

This SOD2 antibody is generated from rabbits immunized with human recombinant SD protein.

Isotype

Rabbit Ig

GeneID

UniProt ID

Function

Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.

Summary

SOD2 is a member of the iron/manganese superoxide dismutase family. It is a mitochondrial protein that forms a homotetramer and binds one manganese ion per subunit. This protein binds to the superoxide byproducts of oxidative phosphorylation and converts them to hydrogen peroxide and diatomic oxygen. Mutations in this gene have been associated with idiopathic cardiomyopathy (IDC), premature aging, sporadic motor neuron disease, and cancer.

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, FC, E

Dilution

WB~~1:1000 FC~~1:10~50

Synonyms

Superoxide dismutase [Mn], mitochondrial, SOD2

Images

Western blot analysis of anti-SOD2 Pab (Cat. AP7979a) in K562 cell line lysates (35ug/lane). SOD2(arrow) was detected using the purified Pab.

SOD2 Antibody (Cat. APR07183G) flow cytometric analysis of NCI-H460 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Specification

Quantity

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