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CYP2J2 Antibody (Center)

Catalog # Availability Size / Price Inquiry
APG02900G 100 μl / $495

CYP2J2 Antibody (Center)

Brand

Leading Biology

Catalog Number

APG02900G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CYP2J2 antibody (Center).

Molecular Weight

57611 Da

Cellular Localization

Antigen Cellular Localization: Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein

Host

Rabbit

Species Reactivity

Human

Immunogen

156-183 aa

Target

This CYP2J2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 156-183 amino acids from the Central region of human CYP2J2.

Isotype

Rabbit Ig

GeneID

UniProt ID

Function

This enzyme metabolizes arachidonic acid predominantly via a NADPH-dependent olefin epoxidation to all four regioisomeric cis-epoxyeicosatrienoic acids. One of the predominant enzymes responsible for the epoxidation of endogenous cardiac arachidonic acid pools.

Summary

CYP2J2 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is thought to be the predominant enzyme responsible for epoxidation of endogenous arachidonic acid in cardiac tissue.

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, E

Dilution

WB~~1:1000 IHC-P~~1:10~50

Synonyms

Cytochrome P450 2J2, Arachidonic acid epoxygenase, CYPIIJ2, CYP2J2

Images

Western blot analysis of anti-CYP2J2 Antibody (Center) (Cat. AP7540c) in CEM cell line lysates (35ug/lane). CYP2J2 (arrow) was detected using the purified Pab.

CYP2J2 Antibody (Center)(Cat. APG02900G) immunohistochemistry analysis in formalin fixed and paraffin embedded human skeletal muscle followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the CYP2J2 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.

Specification

Quantity

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