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Location: Home > Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > Aromatase (CYP19A1) Antibody (Center)

Aromatase (CYP19A1) Antibody (Center)

Catalog # Availability Size / Price Inquiry
APG01995G 100 μl / $495

Aromatase (CYP19A1) Antibody (Center)

Brand

Leading Biology

Catalog Number

APG01995G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Aromatase (CYP19A1) antibody (Center).

Molecular Weight

57883 Da

Cellular Localization

Antigen Cellular Localization: Membrane; Peripheral membrane protein.

Host

Rabbit

Species Reactivity

Human

Immunogen

221-253 aa

Target

This Aromatase (CYP19A1) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 221-253 amino acids from the Central region of human Aromatase (CYP19A1).

Isotype

Rabbit Ig

Symbol

ARO1, CYAR, CYP19

GeneID

UniProt ID

Function

Catalyzes the formation of aromatic C18 estrogens from C19 androgens.

Summary

CYP19A1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids.This protein localizes to the endoplasmic reticulum and catalyzes the last steps of estrogen biosynthesis, three successive hydroxylations of the A ring of androgens. Mutations in this gene can result in either increased or decreased aromatase activity; the associated phenotypes suggest that estrogen functions both as a sex steroid hormone and in growth or differentiation.

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Dilution

WB~~1:1000

Synonyms

Aromatase, CYPXIX, Cytochrome P-450AROM, Cytochrome P450 19A1, Estrogen synthase, CYP19A1, ARO1, CYAR, CYP19

Images

Western blot analysis of anti-CYP19A1(Center) Pab (Cat. APG01995G) in HL60 cell line lysates (35ug/lane). CYP19A1(arrow) was detected using the purified Pab.

Specification

Quantity

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