> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > CCRK Antibody (N-term)Brand |
Leading Biology | Catalog Number |
APR15310G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality CCRK antibody (N-term).
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Molecular Weight |
38695 Da
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Cellular Localization |
Antigen Cellular Localization:
Nucleus. Cytoplasm. Cell projection, cilium
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Host |
Rabbit
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Species Reactivity |
Human
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Immunogen |
16-45 aa
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Target |
This CCRK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 16-45 amino acids from the N-terminal region of human CCRK.
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Isotype |
Rabbit Ig
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Symbol |
CCRK, CDCH
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GeneID |
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UniProt ID |
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Function |
Required for high-level Shh responses in the developing neural tube. Together with TBC1D32, controls the structure of the primary cilium by coordinating assembly of the ciliary membrane and axoneme, allowing GLI2 to be properly activated in response to SHH signaling (By similarity). Involved in cell growth. Activates CDK2, a kinase involved in the control of the cell cycle, by phosphorylating residue 'Thr-160'.
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Summary |
CCRK contains a kinase domain most closely related to the cyclin-dependent protein kinases. This protein is involved in cell growth and activates CDK2, a kinase involved in the control of the cell cycle, by phosphorylating residue Thr-160.
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Form |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, E
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Dilution |
WB~~1:1000
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Synonyms |
Cyclin-dependent kinase 20, CDK-activating kinase p42, CAK-kinase p42, Cell cycle-related kinase, Cell division protein kinase 20, Cyclin-dependent protein kinase H, Cyclin-kinase-activating kinase p42, CDK20, CCRK, CDCH
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Images |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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