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SPCS3 Antibody (C-term)

Catalog # Availability Size / Price Inquiry
AMM07954G 100 μl / $495

SPCS3 Antibody (C-term)

Brand

Leading Biology

Catalog Number

AMM07954G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality SPCS3 antibody (C-term).

Molecular Weight

20313 Da

Cellular Localization

Antigen Cellular Localization: Microsome membrane; Single- pass type II membrane protein. Endoplasmic reticulum membrane; Single-pass type II membrane protein

Host

Rabbit

Species Reactivity

Human, Mouse

Immunogen

152-180 aa

Target

This SPCS3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 152-180 amino acids from the C-terminal region of human SPCS3.

Isotype

Rabbit Ig

Symbol

SPC22

GeneID

UniProt ID

Function

Component of the microsomal signal peptidase complex which removes signal peptides from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum.

Summary

SPCS3 is a component of the microsomal signal peptidase complex which removes signal peptides from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum.

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, FC, E

Dilution

WB~~1:1000 IHC-P~~1:50~100 FC~~1:10~50

Synonyms

Signal peptidase complex subunit 3, 34--, Microsomal signal peptidase 22/23 kDa subunit, SPC22/23, SPase 22/23 kDa subunit, SPCS3, SPC22

Images

Western blot analysis of SPCS3 antibody (C-term) (Cat. AMM07954G) in mouse liver tissue lysates (35ug/lane). SPCS3 (arrow) was detected using the purified Pab.

Formalin-fixed and paraffin-embedded human hepatocarcinoma reacted with SPCS3 Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

SPCS3 Antibody (C-term)(Cat. AMM07954G) flow cytometry analysis of HepG2 cells (bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Specification

Quantity

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