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DSCR1L1 Antibody (N-term)

Catalog # Availability Size / Price Inquiry
APR11269G 100 μl / $495

DSCR1L1 Antibody (N-term)

Brand

Leading Biology

Catalog Number

APR11269G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality DSCR1L1 antibody (N-term).

Molecular Weight

21997 Da

Host

Rabbit

Species Reactivity

Human, Mouse

Immunogen

6-37 aa

Target

This DSCR1L1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 6-37 amino acids from the N-terminal region of human DSCR1L1.

Isotype

Rabbit Ig

Symbol

DSCR1L1, ZAKI4

GeneID

UniProt ID

Function

Inhibits calcineurin-dependent transcriptional responses by binding to the catalytic domain of calcineurin A. Could play a role during central nervous system development.

Summary

DSCR1L1 inhibits calcineurin-dependent transcriptional responses by binding to the catalytic domain of calcineurin A. This protein may play a role during central nervous system development. Expression is detected in fibroblasts, heart, brain, liver, and skeletal muscle but not in placenta, lung, kidney and pancreas. Expression of both transcripts is upregulated by physiologic concentrations of the thyroid hormone triiodothyroxine.

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, FC, E

Dilution

WB~~1:1000 IHC-P~~1:10~50 FC~~1:10~50

Synonyms

Calcipressin-2, Down syndrome candidate region 1-like 1, Myocyte-enriched calcineurin-interacting protein 2, MCIP2, Regulator of calcineurin 2, Thyroid hormone-responsive protein ZAKI-4, RCAN2, DSCR1L1, ZAKI4

Images

DSCR1L1 Antibody (Q21) (Cat. APR11269G) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the DSCR1L1 antibody detected the DSCR1L1 protein (arrow).

DSCR1L1 Antibody (Q21) (Cat. APR11269G) western blot analysis in mouse heart tissue lysates (35ug/lane).This demonstrates the DSCR1L1 antibody detected the DSCR1L1 protein (arrow).

DSCR1L1 antibody (N-term) (Cat. APR11269G)immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of DSCR1L1 antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.

Specification

Quantity

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