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TRAM2 Antibody (C-term)

AMM08323G Product Datasheet Protocol

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AMM08323G		100 μl / $495

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Leading Biology Inc.

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TRAM2 Antibody (C-term)

Brand	Leading Biology	Catalog Number	AMM08323G
Product Type	Polyclonal Antibodies	Field of Research
Product Overview	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality TRAM2 antibody (C-term).
Molecular Weight	43328 Da
Cellular Localization	Antigen Cellular Localization: Membrane; Multi-pass membrane protein
Host	Rabbit
Species Reactivity	Human
Immunogen	342-370 aa
Target	This TRAM2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 342-370 amino acids from the C-terminal region of human TRAM2.
Isotype	Rabbit Ig
Symbol	KIAA0057
GeneID	9697
UniProt ID	Q15035
Function	Necessary for collagen type I synthesis. May couple the activity of the ER Ca(2+) pump SERCA2B with the activity of the translocon. This coupling may increase the local Ca(2+) concentration at the site of collagen synthesis, and a high Ca(2+) concentration may be necessary for the function of molecular chaperones involved in collagen folding.
Form	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Storage & Stability	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Applications	WB, IHC-P, E
Dilution	WB~~1:1000 IHC-P~~1:50~100
Synonyms	Translocating chain-associated membrane protein 2, TRAM2, KIAA0057
Images	TRAM2 Antibody (C-term) (Cat. AMM08323G) western blot analysis in MDA-MB231 cell line lysates (35ug/lane).This demonstrates the TRAM2 antibody detected the TRAM2 protein (arrow). TRAM2 antibody (C-term) (Cat. AMM08323G) immunohistochemistry analysis in formalin fixed and paraffin embedded human prostate carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the TRAM2 antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
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