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KCNJ6 Antibody (Center)

Catalog # Availability Size / Price Inquiry
AMM06130G 100 μl / $495

KCNJ6 Antibody (Center)

Brand

Leading Biology

Catalog Number

AMM06130G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality KCNJ6 antibody (Center).

Molecular Weight

48451 Da

Cellular Localization

Antigen Cellular Localization: Membrane; Multi-pass membrane protein.

Host

Rabbit

Species Reactivity

Human

Immunogen

26-55 aa

Target

This KCNJ6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 26-55 amino acids from the Central region of human KCNJ6.

Isotype

Rabbit Ig

Symbol

GIRK2, KATP2, KCNJ7

GeneID

UniProt ID

Function

This potassium channel may be involved in the regulation of insulin secretion by glucose and/or neurotransmitters acting through G-protein-coupled receptors. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium.

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, FC, E

Dilution

WB~~1:1000 IHC-P~~1:50~100 FC~~1:10~50

Synonyms

G protein-activated inward rectifier potassium channel 2, GIRK-2, BIR1, Inward rectifier K(+) channel Kir32, KATP-2, Potassium channel, inwardly rectifying subfamily J member 6, KCNJ6, GIRK2, KATP2, KCNJ7

Images

KCNJ6 Antibody (Center) (Cat. AMM06130G) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the KCNJ6 antibody detected the KCNJ6 protein (arrow).

KCNJ6 Antibody (Center) (Cat. AMM06130G) immunohistochemistry analysis in formalin fixed and paraffin embedded human pancreas tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the KCNJ6 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.

KCNJ6 Antibody (Center) (Cat. AMM06130G) flow cytometric analysis of K562 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Specification

Quantity

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